Bootstrap follows common web standards and—with minimal extra effort—can be used to create sites that are accessible to those using AT.
If your navigation contains many links and comes before the main content in the DOM, add a Skip to main content link immediately after your opening <body> tag. (read why)
If your navigation contains many links and comes before the main content in the DOM, add a Skip to main content link before the navigation (read why). Using the .sr-only class will visually hide the skip link, and the .sr-only-focusable class will ensure that the link becomes visible once focused (for sighted keyboard users).