diff --git a/README.rst b/README.rst
index 43dae7b..7fe170f 100644
--- a/README.rst
+++ b/README.rst
@@ -39,7 +39,6 @@ You can test against multiple versions of Python with
 
 Versions currently tested in both tox and Travis CI are:
 
-* CPython 2.6
 * CPython 2.7
 * CPython 3.4
 * CPython 3.5
diff --git a/setup.py b/setup.py
index 7c7976d..28f403b 100755
--- a/setup.py
+++ b/setup.py
@@ -7,6 +7,7 @@ except ImportError:
 setup(
     name='contextlib2',
     version=open('VERSION.txt').read().strip(),
+    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*',
     py_modules=['contextlib2'],
     license='PSF License',
     description='Backports and enhancements for the contextlib module',